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The 8 Best Flea and Tick Medications for Dogs in 2024, Recommended by Vets

Fleas and ticks are year-round parasites prevalent throughout most of the U.S., bringing discomfort and diseases such as anemia, Lyme disease, and Rocky Mountain Spotted Fever. Preventing these parasites is crucial for your dog's health. No matter where you live, your dog should be on flea and tick preventatives all year round—even during the winter.

Our veterinarian panel rounded up their top choices for the best flea and tick medications based on their clinical observations, effectiveness, safety, cost, and other factors.

Best Flea and Tick Medications for Dogs What To Look For in Flea and Tick Products for Dogs

When selecting the right flea and tick preventative for your pup, it’s important to chat with your vet first. They can help you find the best flea and tick preventative depending on your dog’s lifestyle and whether a capsule, chew, or topical preventative would be better suited. Some flea and tick options also offer additional benefits, such as protection against heartworms or hookworms, Best Flea and Tick Medications for Dogs

Top Flea and Tick Medications for 2024

1. Simparica® Chewable Tablet

Our Vet Pick: Best in Show

Simparica is highly effective against fleas and ticks and is more cost-effective than many other medications on the market. It must be given on time and once a month to work effectively and doesn’t need to be given with food. The liver-flavored chew is often seen as a treat by dogs.

Things to Consider:

  • Highly effective

  • Easy to administer

  • Safe for dogs 2.8 pounds and up

  • Once-a-month chewable tablet

  • Prescription required

  • FDA-approved

2. NexGard® Chew for Dogs

Our Vet Pick: Best Chew

NexGard Chews are effective against fleas and most ticks, killing existing fleas within eight hours. It’s FDA-approved to help prevent Lyme infections in dogs and is suitable for puppies at least 8 weeks old and weighing 4 pounds or more.

Things to Consider:

  • Kills existing fleas within eight hours

  • Tasty and easy to administer

  • FDA-approved

  • Prescription required

3. Bravecto® Topical Solution

Our Vet Pick: Best Topical

Bravecto Topical Solution lasts up to 12 weeks and kills fleas and ticks within the first 12 hours. It’s an ideal choice for dogs that don’t like oral medications. Ensure the medication is completely dry before allowing contact with other pets or children.

Things to Consider:

  • Offers up to three months of protection

  • Kills fleas and ticks within 12 hours

  • Easy to administer

  • FDA-approved

  • Prescription required

4. Comfortis™ Chewable Tablet

Our Vet Pick: A Safer Flea and Tick Option

Comfortis is potentially safer for dogs that experience seizures. It protects against flea infestations and is highly effective, killing 100% of fleas in just four hours. However, it does not prevent tick infestations.

Things to Consider:

  • Safer for dogs with a history of seizures

  • Protects against fleas

  • Does not prevent tick infestations

  • FDA-approved

  • Prescription required

5. Seresto® Flea and Tick Collar

Our Vet Pick: Best Collar

The Seresto collar repels and kills ticks and fleas for up to eight months, making it a budget-friendly option. It is water-resistant and does not require a prescription, but ingestion can pose safety risks.

Things to Consider:

  • Lasts up to eight months

  • Water-resistant

  • Budget-friendly

  • No prescription required

6. Capstar® Flea Oral Treatment

Our Vet Pick: Best for Infestations

Capstar is a fast-acting medication that kills fleas within 30 minutes. It is a short-term solution for flea infestations and is best used in conjunction with a long-term flea and tick preventative.

Things to Consider:

  • Fast-acting

  • No prescription required

  • Only kills adult fleas

  • Effects last only 24 hours

  • FDA-approved

7. Revolution Topical Solution for Dogs

Our Vet Pick: Great for Puppies

Revolution is safe for puppies as young as 6 weeks old and dogs under 5 pounds. It protects against fleas, ticks, heartworms, ear mites, and intestinal parasites. Ensure the medication is completely dry before allowing contact with other pets or children.

Things to Consider:

  • Safe for young puppies

  • Protects against multiple parasites

  • Limited tick coverage

  • Prescription required

8. Advantage™ Flea and Tick Shampoo

Our Vet Pick: Best Shampoo

Advantage Flea and Tick Shampoo is effective for killing fleas and ticks on contact. It is ideal for pets and pet parents sensitive to fragrances. However, it should not be used as a substitute for monthly preventatives.

Things to Consider:

  • Kills fleas and ticks on contact

  • Unscented formula

  • Can’t be used on puppies younger than 12 weeks

  • Should not be used in households with cats

Q&A Section

Q: How often should I give my dog flea and tick preventatives?A: Most flea and tick preventatives are given monthly, but some, like Bravecto, can last up to three months. Follow the manufacturer’s directions and your vet’s recommendations.

Q: Can my dog still get fleas and ticks while on preventative medication?A: While preventatives greatly reduce the risk, no medication is 100% effective. Regular use and proper application are crucial.

Q: What should I do if I miss a dose of my dog’s flea and tick medication?A: Administer the missed dose as soon as you remember and adjust the dosing schedule accordingly. Consult your vet for specific guidance.

FAQ Section

Q: Can flea and tick medications be used on puppies?A: Yes, but age and weight requirements vary by product. Always follow the manufacturer’s guidelines and consult your vet.

Q: Are flea and tick collars effective?A: Yes, collars like Seresto can provide long-lasting protection. Ensure proper fit and monitor for any adverse reactions.

Q: Can I use flea and tick shampoos instead of monthly preventatives?A: Shampoos are a temporary solution and should not replace monthly preventatives. They are useful for immediate relief but do not offer long-term protection.


Choosing the right flea and tick medication for your dog is crucial for their health and well-being. Consult your veterinarian to find the best product suited to your dog's needs and lifestyle. Regular use and adherence to dosing schedules will help keep your furry friend safe from these pesky parasites.

For more tips and product recommendations, visit Ensuring your dog's health will contribute to a happier, healthier life for your beloved pet.

Best Flea and Tick Medications for Dogs
Best Flea and Tick Medications for Dogs


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